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A modified triple combination cream consisting of hydroquinone, a retinoid, and a low-potency steroid have been considered as a therapeutic regimen for melasma management

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These systems metabolize and scavenge for reactive oxygen species, in a controlled and precise fashion

A key focus is placed on the dysregulation of the kynurenine pathway of tryptophan metabolism, which mechanistically links immune activation to neurotransmitter imbalances

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