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Several signaling pathways in response to ANG II are mediated by reactive oxygen species (ROS) (78), whose production is increased by ANG II in different cell types through Nox4 (NADPH [Nicotinamide adenine dinucleotide phosphate] oxidase 4) stimulation (79), cardiac hypertrophy (80), and diabetic nephropathy (81)

10.1016/j.metabol.2021.154734 3 EbrahimN.ShakirovaK.DashinimaevE

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Currently, marketed antifungal drugs have undergone extensive structural modifications and modifications