Bone , 24 3, 195-202
This extended duration of action made exendin-4 a promising candidate for therapeutic development
Gastrointestinal Protection Extensive Research Extensive research demonstrates powerful cytoprotective properties throughout the gastrointestinal tract, with studies showing protection against NSAID-induced gastric lesions, alcohol-induced stomach damage, and stress ulcers
Notably, this study included broad range of GLP-1 drugs, including much older GLP-1s that have far lower anti-obesity, anti-craving, and anti-addictive effects: abiglutide (Eperzan, Tanzeum), dulaglutide (Trulicity), exenatide (Byetta, Bydureon), liraglutide (Victoza, Saxenda), lixisenatide (Adlyxin, Lyxumia), semaglutide (Ozempic, Rybelsus, Wegovy) and tirzepatide (Mounjaro) Its possible that the associations that were found would be even stronger if the study had looked exclusively at semaglutide and tirzepatide, which are the current best-in-class options for weight loss
Fras, J.P
Details are provided in the Table 1