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Tirzepatides sequence includes two aminoisobutyric acid (Aib) residues at positions 2 and 13 (non-natural amino acids that enhance proteolytic resistance ), an N-terminal tyrosine (Tyr1) , and a C-terminal amidation for stability

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La extrapolacin de estas dosis al ser humano, utilizando los factores de conversin alomtricos estndar (factor de 6,2 para la rata), da dosis tericas del orden de 1,6 g/kg en humanos