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novembre 2023;36(11)

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Moreover, islets extracted from high cholesterol-fed mice showed decreased exendin-4-induced cAMP responses ex vivo (Supplementary Figure 1A), suggesting a direct impact of increased cholesterol levels on GLP-1R signalling

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GIPR receptors, another gut hormone, are associated with enhancing insulin secretion after nutrient ingestion and promoting lipid storage, which have been said to play a role in weight management