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Because phentermine increases norepinephrine, dopamine, and serotonin, some patients experience anxiety or irritability particularly in the first few weeks as the body adjusts

Patients who may derive particular benefit include: Individuals with type 2 diabetes and mixed dyslipidaemia : Those with elevated triglycerides and modest LDL cholesterol elevation alongside diabetes may experience improvements in multiple cardiovascular risk factors simultaneously

Worse, prolonged elevation of IGF1 levels can increase health risks

Furthermore, the ASD group exhibited a significantly higher Gln/Glu ratio compared to controls, which was negatively correlated with both Sensory Sensitivity and Sensation Avoiding subscales

On the bright side, supporting the gut with probiotics often helps them tolerate higher-histamine foods over time

2012;7(6):e38901