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Oral doses of 510mg/kg in rodent studies achieve measurable CNS concentrations within 30 minutes, with a plasma half-life of approximately 34 hours and brain tissue half-life extending to 68 hours due to lipophilic partitioning into neural membranes

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mPFC: medial Prefrontal Cortex

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It is studied in laboratory research for its role in fat oxidation, lipolysis, adipose tissue metabolism, lipogenesis inhibition, and cartilage repair pathway biology without the IGF-1 stimulation, insulin resistance, or receptor-mediated proliferative effects associated with full-length hGH

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