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I asked that question when I first learned about this process, too, and the answer is pretty interesting

A GLP-1 drug in pill form no needles required helped people with obesity and Type 2 diabetes lose 10% of their body weight and lower their blood sugar levels, pharmaceutical giant Eli Lilly announced on Tuesday, August 26

One 2023 study in Circulation even found that clearing senescent cells, including with FOXO4-DRI, worsened pulmonary hypertension in rodents

Retatrutide's approximately 6-day half-life is what makes once-weekly dosing appropriate

Just as importantly, the symptoms patients attribute to "low GH" fatigue, poor recovery, low energy overlap heavily with hypothyroidism, depression, sleep apnea, and low testosterone, so those causes should be ruled out first

Lastly, unbiased research on the GOLO Diet is lacking as the only available studies are directly funded and conducted by its creators