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Rapid weight loss reduces leptin and oestrogen production from adipose tissue, which can disrupt the hypothalamic-pituitary-ovarian axis

It is a glucagon-like peptide-1 (GLP-1) receptor agonist that helps improve glycemic control, delay gastric emptying, and reduce appetite by lowering glucagon secretion

If patients experience significant gastrointestinal side effects at any stage, the dose escalation may be delayed by an additional four weeks at the current dose level

Both require weekly injections that you give yourself at home using pre-filled pen devices

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