Many athletes use periodic REGEN cycles (4-6 weeks every 4-6 months) for ongoing injury prevention and recovery optimization
They may be considered as part of dual or triple therapy when specific criteria are met, including BMI thresholds (35 kg/m or 32.5 kg/m in certain ethnic groups) and when weight loss would benefit other obesity-related comorbidities
10.1016/0165-6147(91)90609-v [DOI] [PubMed] [Google Scholar] Hardy J., Selkoe D
Pigment International, juin 2017, pages 3-6 5
Pre-clinical research has shown that gingerol potentiates GLP-1 activity , and facilitates glucose uptake in skeletal muscles through increased activity of glycogen synthase 1 and enhanced cell surface presentation of GLUT4 transporters, 16,17 proteins that play a central role in regulating blood glucose levels by facilitating the transport of glucose across the cell membrane
This synergistic weight reduction improves insulin sensitivity further, creating a self-reinforcing cycle of metabolic improvement that extends beyond simple glucose control to address obesity-related complications