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doi: 10.4236/aim.2022.1212044 [DOI] [Google Scholar] 82.Wolfram T, Schwarz M, Reuss M, et al

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57: 3944, doi: Jaworska K, Huc T, Samborowska E, Dobrowolski L, Bielinska K, Gawlak M, Ufnal M

4 To preserve your existing muscle mass: Prioritise protein: Ensure your body has the amino acids required for maintenance

Leptin also enhances ECM accumulation by regulating MMPs/TIMPs system, through the activation of MAPKs such as ERK and p38 pathways that lead to the suppression of collagen-degrading enzymes MMP-1 expression while upregulation of its inhibitor TIMP-1 [171, 172]