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Because the number of trials within several strata was limited, these subgroup estimates and between-group comparisons should be interpreted cautiously

J Pharmacog Phytochem 2018;7(5):2785-9

However, there were minimal effects on TNF-, another inducer of cachexia, in the in vivo model

In contrast, the conjugated forms of the drugs, such as conjugated TubBH (EC 1456) produce anti-tumor responses without significant toxicity to mice bearing well-established human tumor xenografts