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Regarding the intrinsic structure of intestinal bacteria, lipopolysaccharide (LPS) is a major component within the cell wall of gram-negative bacteria (61)

These future studies should address the uncertainties raised in previous evidence, particularly regarding the role of GLP-1 in disease progression, its mechanism of action, and its safety profile, to further clarify the potential of GLP-1 receptor agonists as a therapeutic option in PD

ElAdl, K., Sakr, H., Nasser, M., Alswah, M

This is an excellent question

Disruptions of this microbialendocrine axis, whether through dysbiosis, inflammation, or lifestyle factors, can therefore uncouple hormonal signals from their expected metabolic effects [70,71]

They are found in trace amounts and are not known to be harmful