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## How to Choose: A Decision Framework **Choose Semaglutide if** you want the most established safety profile, cardiovascular protection matters to you (SELECT trial data), you prefer the most affordable compounded option, or you are new to GLP-1 therapy and want a well-studied starting point

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For example, a percent use requirement can be added to confirm a patient has utilized most of their existing supply of a GLP-1 prior to issuing an automated PA approval

Besides, toxins (such as the use of cannabis) and medications (antibiotics, NSAID, laxatives, hormones) need to be excluded

These foods create inflammation in the body that leads to oxidative stress