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If you are managing semaglutide constipation , dehydration compounds both problems simultaneously

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You might notice your face appears sharper, your jawline more defined, or your midsection noticeably smaller while your overall weight changes only modestly

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3 Coupled with the metabolic benefits of this drug, the Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes (SELECT) trial showed a 20% reduction in major cardiovascular events with Semaglutide, making it the only weight loss medication to do so