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The relationship between miRNA-122 elevation and mechanisms of APAP toxicity remains unclear

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A rare WNT1 missense variant overrepresented in ASD leads to increased WNT signal pathway activation

however, when they appear, an investigation of different factors should take place, including mycotoxin analysis, as oral lesions may have other causes

Compounds used for in vivo experiments were further purified by size exclusion chromatography using a HiLoad Superdex 200 pg column (GE Healthcare) and further characterised for endotoxin level using the LAL Kinetic-QCL (Lonza) and integrity by LC/MS using an Acquity UPLC system coupled to a Synapt G1 mass spectrometer (Waters)

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