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A Mendelian randomization study in Frontiers in Endocrinology found that genetically predicted higher insulin resistance was associated with worse cognitive performance, with changes in brain cortical structure mediating part of the effect

Physical Exam A digital rectal exam (DRE) is often the next step

Berberine It is a plant-based supplement

Another systematic review and meta-analysis likewise found acetyl-L-carnitine effective in reducing peripheral neuropathic pain, especially due to diabetes

These treatments work alongside traditional hormone replacement to support cellular health and help your body function more efficiently as you age

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