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Supporting healthy immune system function

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Abstract Many local and systemic diseases especially diseases that are leading causes of death globally like chronic obstructive pulmonary disease, atherosclerosis with ischemic heart disease and stroke, cancer and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 19 (COVID-19), involve both, (1) oxidative stress with excessive production of reactive oxygen species (ROS) that lower glutathione (GSH) levels, and (2) inflammation

In adult T-cell leukemia/lymphoma (ATLL), ART induced intracellular ROS- and iron-dependent cytotoxicity, which was partly inhibited by treatment with an iron chelator or ferroptosis inhibitor (Markowitsch et al., 2020)