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In Parkinsons disease models, melatonin protects dopaminergic neurons from toxin-induced death, likely by reducing oxidative stress and inhibiting apoptotic pathways (Hu et al., 2023

[5] Apart from true vitamin B allergy (which is rare), there are no absolute contraindications in the general population, because pyridoxine is an essential nutrient

Some research suggests copper peptides may also have modest direct effects on DHT activity at the follicle level, but this is less established than the antioxidant mechanism, and human clinical data on this specific point are limited [1]