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Oxidative stress occurs from normal cellular processes but increasingly from pollution, toxins, stress, and other exposures of modern life
High GST activity has been associated with cancer prevention [114]
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Revisiting the scavenging activity of glutathione: Free radicals diversity and reaction mechanisms
Adsorptive-mediated transport at the BBB has also been exploited to target nanocarrier systems by using cationic lipids and cell penetrating peptides to increase binding and internalization at the brain capillary endothelium [29, 30], which has a highly negative surface charge [31]
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