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Summary Keywords acetyl-L-carnitine, ketamine, regional cerebral metabolic rates for glucose, pain, depression Citation Freo U, Brugnatelli V, Turco F and Zanette G (2021) Analgesic and Antidepressant Effects of the Clinical Glutamate Modulators Acetyl-L-Carnitine and Ketamine

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This is, then, oxidized by cytosolic isocitrate dehydrogenase 1 (IDH1) to -ketoglutarate with the production of NADPH required for the detoxification from reactive oxygen species (ROS

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