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Presentation: Lyophilized powder (research use) Target: Nicotinamide Nmethyltransferase (NNMT) inhibitor Suggested Use: In vitro / preclinical workflows as defined by protocol Storage: Follow validated lab SOPs for smallmolecule lyophilizates 1

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doi: 10.1080/01635581.2021.2007962 137

There are multiple reasons for aging, but the main ones are: damage to DNA, so our genetic information is misread (cells divide with genetic code errors), shortening of telomeres, and accumulation of senescent cells (zombie cells, that stopped dividing, but did not die) and senescent cells affect neighbor cells, stopping them to divide (produce more zombie cells) , converting healthy cells into senescent prematurely

Research by Anisimov and colleagues demonstrated that Epithalon markedly inhibited tumor development and reduced the maximum size of breast adenocarcinomas in transgenic mice, while other studies showed delayed metastasis development from spontaneous tumors