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Only patients who tolerated the final dose of rosiglitazone (8 mg/day) and metformin (2,000 mg/day) and completed the 6-week dose maintenance phase were eligible for randomization into the trial

Arch Dis Child Fetal Neonatal Ed

The pain from the nerve damage can be severe with tingling or numbness in the part of the body

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It significantly upregulated markers such as MAP2, GAP43, and AGBL4, all of which are associated with neuronal development, axonal growth, and synaptic remodeling