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In rare cases, more serious side effects can develop

Some studies have reported no significant differences in IGF-1 levels or side effects following interventions such as lycopene supplementation or calorie restriction, suggesting a lack of direct effect in certain cases

It has been suggested that GSTP1 also protects cells from oxidants and electrophilic-mediated genomic damage (29)

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Cycling: 8 Weeks On, 8 Weeks Off Community protocols describe 500 mcg daily for 8 weeks straight, then 8 weeks off before repeating