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high proportions of patients achieve sustained low disease activity or remission One of the major pitfalls of biologic TNF inhibition is the occurrence of infectious complications (common or opportunistic) Other shortcomings of current anti-TNF biologics include high costs, inadequate numbers of treated patients achieving sustained, high-magnitude responses or remission and secondary loss of efficacy over time This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues and online access 189,00 per year only 15,75 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF

Emerging trends show that graphene-based nanomaterials develop unique properties and can be employed for biomedical applications, particularly in drug delivery and tissue engineering (Zhu et al., 2010)

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Cysteine/Glutathione Deficiency: A Significant and Treatable Corollary of Disease

The regulation of BBB permeability by various transporters has been extensively discussed elsewhere [31]

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