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Pain or Tenderness at the Injection Spot Lipotropic injections are sent into the body through a needle, and following the injection, it is possible to experience some pain and tenderness at the point of injection

When to See a Doctor There are also more serious side effects from getting a vitamin B12 shot

Pernicious anemia is an absorption failure caused by loss of intrinsic factor, usually autoimmune

Retatrutide (a triple GIP/GLP-1/glucagon receptor agonist), survodutide, mazdutide, and CagriSema represent the next generation of anti-obesity compounds that may offer even greater efficacy or better tolerability profiles

The use of NNMT inhibitors as a potential obesity treatment has been investigated preclinically 8,9,13 , and observational clinical data suggests that increased NNMT expression and activity correlate with increased incidence of Type 2 diabetes (T2D) and risk of obesity, respectively 10,11

PMID 23356638