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Protein tyrosine phosphatase 1B as a therapeutic target for Graves' orbitopathy in an in vitro model

Anatomical proximity to radiosensitive organs such as the bladder, rectum, and bowel restricts dose escalation and exposes patients to long-term toxicities including fibrosis, necrosis, sexual dysfunction, and urinary or bowel complications [14,15,16]

For those taking GLP-1 medications, this type of diet can minimize common side effects like nausea and bloating, while promoting better long-term digestive and metabolic health

Absence of pRb facilitates E2F1-induced cell death in breast cancer cells

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Despite these promising attributes, significant challenges remain