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Liver serine palmitoyltransferase activity deficiency in early life impairs adherens junctions and promotes tumorigenesis

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When the heart cannot pump enough blood, its known as heart failure

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It is a major cellular antioxidant, involved in defense against oxidative stress and redox signaling

However, at present, clinical adverse effect data specific to breast cancer treatment settings remain limited, and the available human evidence is derived mainly from cancer risk analyses rather than oncology-focused intervention studies