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Controlled freezing studies of recombinant hGH demonstrated that insoluble particulate aggregation increases sharply with cooling rate, with pH 7.4 formulations producing markedly more light-scattering particulates than pH 7.8 formulations after freeze-thaw (Eckhardt, Oeswein & Bewley, 1991)

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Letter of medical necessity

Available from: /pmc/articles/PMC6771702/ Interdisziplinre S3-Leitlinie Prvention und Therapie der Adipositas: Version 2.0 (April 2014) [Internet]

Alexander Shapsis