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Notably, cells treated with P-Mn/TI@mHSA demonstrated a marked reduction in CD86 expression

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Similarly, in a mouse model of neuromyelitis optica spectrum disorder, Tregs accumulate around lesion sites and, more specifically, colocalize with inflammatory microglia and macrophages [160]

During hypoxia or under certain oncogenic conditions, -ketoglutarate could be converted directly to citrate (following a reversed TCA cycle), in order to generate the cytosolic acetyl-CoA when glucose-derived acetyl-CoA is insufficient [34]

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