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McGuinness, L
The organic acids metabolized by lactobacilli not only lower the gastric pH but also inhibit the activity of urease, thereby hindering the growth of H
It also has potent antioxidant and anti-inflammatory effects
And UC is believed to result from the interaction between genetic susceptibility, immune factors, and gut microbiota alteration, leading to abnormal mucosal immune responses and impaired epithelial barrier function
Cancer Prev Res (Phila) 7:835844 Imielinski M, Berger AH, Hammerman PS, Hernandez B, Pugh TJ, Hodis E, Cho J, Suh J, Capelletti M, Sivachenko A, Sougnez C, Auclair D, Lawrence MS, Stojanov P, Cibulskis K, Choi K, de Waal L, Sharifnia T, Brooks A, Greulich H, Banerji S, Zander T, Seidel D, Leenders F, Ansn S, Ludwig C, Engel-Riedel W, Stoelben E, Wolf J, Goparju C, Thompson K, Winckler W, Kwiatkowski D, Johnson BE, Jnne PA, Miller VA, Pao W, Travis WD, Pass HI, Gabriel SB, Lander ES, Thomas RK, Garraway LA, Getz G, Meyerson M (2012) Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing