The cases with an H -score less than the cut-off value were regarded as low GSTM3 expression, while the others were high GSTM3 expression
Dimba et al., 2024)
These studies revealed that statins inhibit gliosis and RGC apoptosis in Mller cells, with TNF- identified as a critical mediator
By contrast, CIBB treatment in the CI-M group significantly reduced the percentage of M1 macrophages (31.81% in the CI-M group) and increased the percentage of M2 macrophages (26.18% in the CI-M group) close to that in the control group

Learn how you can trigger your cells to make their own melatonin Key Points Melatonin has been shown to have antioxidant and anticancer effects, to play a role in the regulation of blood pressure and glucose levels, is highly anti-inflammatory, and has also been shown to lower the risk of SARS-CoV-2 infection and mortality Melatonin exists in two main forms within the body circulatory melatonin, which is produced by the pineal gland and has its major effect on sleep and the circadian rhythm, and subcellular melatonin, which is produced and used locally by the mitochondria within our cells Production of melatonin can be triggered through exposure to the infrared spectrum of light sunshine is our major source of infrared light, but it can also come from exposure to fire (campfire, candle flames, fireplace, etc.) and some red-light therapy Melatonin is a powerful anti-oxidant, and as discussed in the video below, could even be considered more powerful than the Master Antioxidant glutathione, which was reviewed in our last post here

As we can see, maintaining optimal glutathione levels is essential for our well-being