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Similarly, the treatment effect on MCS was reduced when adjusted for HbA1c change

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The most common side effects are nausea, constipation, bloating, and a decrease in appetite

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Lower doses cause fewer side-effects, which is why the recommended dosing schedule starts low and gradually builds up

Thyroid Monitoring Protocol for Patients on Semaglutide Providers typically establish a baseline thyroid panel (TSH, free T4) before starting semaglutide, then recheck levels 8-12 weeks after initiation and periodically thereafter