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The standard approach often begins with a low dose of semaglutide, commonly 0.25 mg weekly for the first four weeks, which serves primarily as an initiation dose to allow physiological adaptation rather than providing significant therapeutic effect

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In order to demonstrate the broad potential of modifying neurexins as a strategy for sustained antidepressant effect, we examine the regulatory mechanisms of neurexins and their biological role in sustained antidepressant effect in this section

10.1007/s11419-021-00597-4 43 RahnemaC

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