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Dual GIP/GLP-1 Agonist Twincretin Research 99%+ Purity Research Use Only Mechanism of Action Studied as a dual agonist of the GIP receptor (GIPR) and GLP-1 receptor (GLP-1R), with biased GLP-1R signaling that reduces -arrestin recruitment relative to native GLP-1

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Activation of GLP-1R in the PVN stimulates the release of oxytocin, which exerts anorexigenic effects [13]

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