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Considering the rapid progress of bispecific antibody based molecules 22 , this lack of clinical data for any peptide-antibody fusion likely reflects the significant technical challenges in the development of such molecules

10.1124/pr.109.002436 35 ManchandaY.BitsiS.ChenS.BroichhagenJ.Bernardino de la SernaJ.JonesB.et al (2023)

Reconstituted peptide must not be frozen, as freeze-thaw cycles damage the molecule

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The advent of ~15% average weight loss drugs has, for the first time, made many clinicians more optimistic about treating obesity as a chronic condition medically

However, its significant cost, often exceeding $1200 per month without insurance, can be a major barrier for many patients