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Higher dose therapies can take up to 3 hours and have to be administered slowly and safely

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A further contributing factor is the trauma caused during the surgery itself, which can create alterations to the skin tone and changes to the appearance of the abdominal area

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Below is a picture of a mom and daughter on the left as well as one of Doctor Paula and her 85-year-old mom on the right

Nature 513 , 5964 (2014)