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Alyssa Dominguez, an endocrinologist at the University of Southern Californias Keck School of Medicine, told Rolling Stone that the doses are super off compared to anything that was in research studies, like they were giving people 8,000 times the dose of what is in the patch. Dr

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We give weekly injections of 1000 mcg (1 ml) of vitamin B12 for the first 4-6 weeks

And because it is derived from a naturally occurring protein, its mechanism of action works with existing biological pathways rather than introducing foreign signaling

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That is frequently 5, 10, or 15 mg escalation stops when the target is met, not automatically at 15 mg