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GHK-Cu is predominantly found in saliva, blood, and urine, and has multiple biological actions when administered to test subjects, including [1]: Antioxidant gene activity [2] Suppression of inflammatory cytokine interleukin-6 [2] Increased protein accumulation [3] Increased collagen synthesis [3] In animal models, GHK-Cu has been shown to increase an anti-inflammatory proteogly called decorin that can protect diabetic rats from kidney-damaging fibrosis [2, 4]
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Dosages used in the reviewed studies ranged from 600 to 3600 mg per day for 8 weeks to 1 year, with studies using dosages of 10002000 mg per day showing the best responses
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However, limited success with these approaches for specific patients suggests a complementary role for dietary supplements and plant-derived adjuncts to potentially enhance treatment efficacy
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