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First, direct pharmacological interactions where one compound changes how another works in the body

By suppressing appetite and reducing cravings, these drugs alter the brain's normal reward responses to food

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Moreover, free phenolic extract from rape BP possesses higher capabilities to defend body cells from aberrant melanogenesis than bound phenolic extract via the suppression of microphthalmia-associated transcription factor (MITF) and downregulation of cyclic adenosine monophosphate (cyclic adenosine monophosphate) while preventing the anti-tyrosinase and antioxidant pathways in vitro (22)

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Trends Food Sci Technol 31(2):118129 Granato D, Nunes DS, Barba FJ (2017) An integrated strategy between food chemistry, biology, nutrition, pharmacology, and statistics in the development of functional foods: a proposal