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IM injection 1,000 mcg/month for severe cases

The compound has been a subject of biochemical investigation since its isolation from human plasma in the 1970s

A drug can not generally have an oral bioavailability value higher than its value for f H , and oral bioavailability can equal f H only when all of the drug escapes from the GI tract and is able to enter the portal circulation (i.e

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Common side effects include mild pain or redness at the injection site, transient headache, and pink-tinged urine due to the red colour of hydroxocobalamin

The Bottom Line GHK-Cu and AHK-Cu are complementary, not competing