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A fusion target-decoy approach was used for the estimation of false discovery rate (FDR) and controlled at 50% in each group were filtered out

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Moreover, also a by-product of ethanol metabolism such as acetaldehyde, which is further oxidised to acetate by mitochondrial aldehyde dehydrogenase, seems to contribute primarily to the alcohol-induced liver diseases by acting at the genomic level through up-regulation of some redox-sensitive transcription factors involved in fibrogen-esis, such as AP-1 and NF-B