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PLoS One 12:e0178748

The study found that maternal weight gain was significantly lower in the metformin group compared to the placebo group, with no significant difference observed in newborn birth weight

As discussed below, the development of unimolecular multi-agonists that stimulate GLP-1 receptors and other receptors such as GIP receptors and glucagon receptors (GCGR) can have beneficial effects on metabolism and increase metabolic rate at tolerable doses [57]