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In children receiving long-term risperidone, the ratio of Bacteroidetes to Firmicutes (two major bacterial groups in the gut) dropped significantly from 1.24 in psychiatric controls to just 0.20 in those who gained a lot of weight

In individuals with low brain folate, the neurological consequencessuch as seizures, motor dysfunction, cognitive impairment, and speech delayscan be more debilitating than the potential downside of increased serotonin clearance

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