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However, there is no official contraindication based solely on heart rate considerations, and these medications can be used safely in most patients with cardiovascular disease under appropriate medical supervision

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It can lead to weight loss, better glycemic control, and reduced cardiometabolic risk factors

has examined a promising therapeutic avenue: glucagon-like peptide-1 receptor agonists (GLP-1 RAs) for stroke prevention

JAMA 2021;325:1414-25.PubMed 117

Multiple meta-analyzes have attempted to consolidate these findings: A systematic review found pooled IBS incidence rates of 12% among COVID-19 patients Cross-sectional studies report prevalence rates of 13% , whereas longitudinal studies show rates of 16% The subtypes distribution shows IBS-D (diarrhea-predominant) at 5% , IBS-C (constipation-predominant) at 2% , and IBS-M (mixed) at 1% The wide variation in reported figuresfrom as low as 0.17% to as high as 20%stems from differing diagnostic standards, with Rome IV criteria yielding substantially lower prevalence estimates than Rome III