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Today Im sitting at 183 lbs with a body fat percentage of 19.4%

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CagriSema's REDEFINE 1 number is competitive against tirzepatide's SURMOUNT-1 figure, but a direct head-to-head trial reported in February 2026 favored tirzepatide

And unlike individual anecdotes, the studies are designed to ensure that any observed benefits are due to the treatment itself and not to the placebo effect

When the elimination half-life is minutes, peptide is being cleared roughly as fast as it is absorbed, and the peak plasma concentration achievable is far below what a bolus IV injection produces