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Their safety and effectiveness haven't been established

Affordable access for 101 million diabetics is genuinely significant

Al-Aly subraya que la reduccin del riesgo es modesta, pero ante la ausencia de un tratamiento de eficacia probada, "esta es sin duda una buena noticia y un gran avance", uno que los investigadores seguirn estudiando

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But berberines glucose-lowering is glucose-dependent, meaning it tends to work harder under hyperglycemic conditions

The pattern across these concerns: the most alarming-sounding risks (cancer, vitiligo, weight gain) have little to no scientific support for standard oral supplementation, while the more mundane, less-discussed side effect (mild headache) is the one with actual documented occurrence