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In our study, we initially generated multiple lines for five LMNA mutants and observed similar larval phenotypes and LMNA expression levels across these lines

Dhillon GS, Brar SK, Kaur S

For this purpose, RAW 264.7 cells, a macrophage cell line obtained from a male mouse tumor induced with Abelson murine leukemia virus, were plated in complete DMEM (Euroclone) supplemented with 10% FBS in 48-well plates at a density of 2 10 5 cells per well

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This creates a metabolic environment that opposes AOD-9604s lipolytic mechanisms

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