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The pharmacological antagonists of MC4R appeared to lead to weight gain, while the agonist was observed to lead to the contrary in laboratory experiments

Neither the thymosin fragment nor the body protection compound contains cysteine or methionine residues

Together, these findings underscore the central role of gutliver axis interactions in ZEN-, fumonisin-, T-2 toxin-, and enniatin-induced hepatotoxicity and support microbiota-targeted strategies as promising approaches to mitigate mycotoxin-induced liver damage (Ben Salah-Abbs et al

limited efficacy data, variable absorption

Slater M, Barden JA, Murphy CR

QJM Int J Med