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Headache, particularly at initiation Mild anxiety or restlessness with some compounds Nasal irritation (intranasal administration) Sleep disturbance if dosed too close to bedtime Rare: Mood changes or emotional lability Dihexa (PNB-0408, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide) is a potent hepatocyte growth factor (HGF) receptor agonist originally developed at Washington State University

Understanding individual response variability Genetic factors: Polymorphisms in genes encoding growth factor receptors, collagen synthesis enzymes, inflammatory mediators affect healing capacity and peptide responsiveness

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(249 characters) Easy dosing for all sizes: For dogs 50 lbs or less, use 0.5 mL once daily